6 Best Whole House Air Purifiers – Reviews and Buying Guide

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Last updatedLast updated: September 07, 2021
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Adding an air purifier to your home can provide a lot of different benefits. They work to clean the air you breathe each day, letting you and the other members of your household lead happier and healthier lives. The best whole house air purifier models are able to clean the air in the entire home, ridding it of dust, allergens, irritants, and pollutants. And despite what you might think, whole house air purifiers don’t have to be super expensive.

We’ve put together a list of the best whole house air purifiers at different prices in order to offer a great selection of products for you to choose from, like the Medify MA-112 Medical Grade True HEPA H13. We spent a lot of time looking at different reviews and considering the various features of each model. We looked at the size and weight of each purifier, as well as the maximum square footage that it can handle, plus the type of filter it uses and any extra features it might have.

Below, you can find a comparison table with all of our findings, showing the list of best whole house air purifiers for you to choose from. Further down the page, you can read through detailed reviews of each air purifier, with pros and cons for each one. Finally, you can take a look at our whole house air purifier buying guide, which takes you through all the reasons for owning an air purifier and the various features to consider.

Top 6 Whole House Air Purifiers Review 2022

  • Type: portable
  • Square footage: 3700 sq ft
  • Cleaning stages: three-in-one
  • Size: 13 x 15 x 28 inches
  • Weight: 32 lbs
  • Filter type: Medical Grade True HEPA
  • Warranty: Lifetime Warranty, is dependent on the use of genuine filters

More features: Touch screen panel, sleep mode and child lock

We’ll start off our list with the Medify MA-112 Medical Grade True HEPA H13. Weighing in at 32 lbs and measuring up at quite a large size, this is one of the biggest and bulkiest models on our list, but it’s also by far one of the most effective. As the name implies, the Medify MA-112 Medical Grade True HEPA H13 really does live up to medical grade standards, offering super effective air cleaning and purifying in a 3-in-1 process.

It can clean up to 3,700 square feet in a single hour, dealing with allergies, smoke, odors, asthma triggers, allergens, dust, and more. It’s fitted with a true HEPA H13 medical grade filter to remove a total of 99.97% of fine particulate matter in the air, working even more effectively than other HEPA type filters. It’s also quite a stylish and modern device, fitted with a touch screen display and useful features like a sleep mode, child lock, and four fan speeds.

Naturally, all of this quality comes at a price, and it’s worth noting that the Medify MA-112 Medical Grade True HEPA H13 is one of the most expensive whole house air purifiers around, but it’s also the best whole house electronic air purifier you can buy right now. It comes with a full, lifetime warranty too, as long as you use the right filters.

What stands out?

  • Huge square footage
  • Medical grade quality
  • Lifetime warranty
  • True HEPA filter
  • Touch screen controls
  • Bonus features like child lock and sleep mode

What cons did we manage to find?

  • Big and heavy
  • Very high price
RELATED: 20 Best Air Purifiers – Your Lungs Deserve Better Air!

Green Air Deluxe 3 Plate HEPABest Air Purifier for Allergies

  • Type: portable
  • Square footage: 3500 sq ft
  • Cleaning stages: Quadruple Filter System
  • Size: 14.7 x 12.4 x 10.8 inches
  • Weight: 16.3 lbs
  • Filter type: Pre-filter, HEPA filter, odor fighting filter, the Photo Catalytic (PCO) filter
  • Warranty: 2-year limited

More features: Separate timer just for the Ozone Function, UV lamp

Arguably the best air purifier for allergies and pets, the Green Air Deluxe 3 Plate HEPA can provide up to 3,500 square feet of coverage, equipped with a 3-plate HEPA filter and odor fighting filter too. Unlike the Medify MA-112, this portable air purifier is highly compact, lightweight, and convenient. It’s easy to carry around the home, letting you move it from one room to another without any hassle.

As well as being compact in its design, the Green Air Deluxe 3 Plate HEPA comes with plenty of great features. It’s equipped with a UV lamp, which helps to eliminate microbes in the air and make your home a safer place for everyone to be, and it features an easy to read LCD display, as well as a range of timers to help you control it precisely and accurately, adjusting the settings and performance however you like. It performs a 4-stage cleaning process too, being super effective at ridding your home of odors, dust, allergens, and other issues.

On the downside, we have to report that some users of the Green Air Deluxe 3 Plate HEPA have complained of it being quite a loud device in operation. Additionally, it works with ozone generation, which can pose a risk to those with pre-existing respiratory problems, so be sure to consult a medical professional if you have breathing problems and want to be sure about your safety when buying this whole house air purifier.

What are our favorite features?

  • Small and compact
  • Easy to move around
  • Comes with a UV lamp for fighting microbes
  • Huge square footage
  • A thorough 4-stage cleaning process
  • LCD display
  • Timers

What could be better?

  • Can get quite loud
  • Ozone generation can pose risks to those with respiratory problems
  • Type: central
  • Square footage: all over the home HVAC system
  • Cleaning stages: 1
  • Size: 28.2 x 17.8 x 6.8 inches
  • Weight: 17 lbs
  • Filter type: genuine Aprilaire Air Filter
  • Warranty: 5-year limited

More features: produce no ozone and are virtually maintenance-free

If you’re looking for the best whole house air purifier but don’t want to pay over the odds, the Aprilaire 2410 Whole-Home Air Cleaner might be the perfect one for you. This is our budget pick for this list, so it’s one of the most affordable models you can hope to find. Rather than being portable, it’s a central unit, so you don’t have the benefit of being able to move it around, but you do get the benefit of minimal maintenance.

The Aprilaire 2410 Whole-Home Air Cleaner requires very minimal care, with the filtering media simply needing to be replaced every 1-2 years. It works to capture over 97% of all airborn pollen-sized particles like dust and allergens. It’s one of the best whole house air purifiers for pets and allergies overall, and it doesn’t produce any ozone, so you don’t have to worry about the associated risks of that.

Installation can be tricky with this model, so you might need the help of a professional, but once you get the Aprilaire 2410 Whole-Home Air Cleaner installed, you won’t need to worry about a thing. It has received lots of 5-star reviews from owners and is one of the most lightweight air purifiers around as well. The only other flaw we could really find with this model is that the 5-year warranty isn’t as long as what we’ve seen with other purifiers.

What do we love it for?

  • Very low maintenance
  • Highly effective against allergens
  • Good for pet owners
  • Very affordable
  • Doesn’t generate any ozone

What were we disappointed with?

  • Tricky installation
  • Quite a short warranty period
RELATED: 20 Best Air Purifiers – Your Lungs Deserve Better Air!

Coway Airmega 400Best Air Purifier for Pets

  • Type: portable
  • Square footage: 1560 sq ft
  • Cleaning stages: 2
  • Size: 14.8 x 14.8 x 22.8 inches
  • Weight: 24.7 lbs
  • Filter type: washable pre-filter; Max2 filter (activated carbon and true HEPA)
  • Warranty: 5-year limited

More features:  timer for 1, 2, 4 and 8 hours, filter life time indicator

A great option for pet owners, the Coway Airmega 400 is another of the best HEPA air purifier for whole house models you can buy. It comes equipped with a true HEPA filter and an activated carbon filter, with these two components working together to clean the house of dust, allergens, and other undesirable elements, as well as making the place smell fresher and cleaner too. It can capture and eliminate up to 99.97% of particles.

The Coway Airmega 400 comes with a lot of different features and functionality, including five different fan modes – Smart, Sleep, Low, Medium, and High. It’s one of the quietest air purifiers around, operating at a maximum of just over 43 db. The Smart mode of this air purifier is particularly effective, letting it automatically adapt its functionality to suit the surroundings, saving energy and letting you simply sit back.

It only comes with quite a short warranty of just one year for malfunctions and five years for parts, and it won’t work so well in larger homes. Apart from these issues, however, the Coway Airmega 400 is a great value air purifier for your home. It features a stylish LED ring that lets you know exactly how clean the air in your home really is, and it’s available in both white and silver models.

What are its best features?

  • Lots of different fan modes
  • Smart setting
  • LED ring lets you know air quality
  • Great for pets and allergies
  • Helps to eliminate odors too

What could be improved?

  • Short warranty period
  • Not the largest square footage
RELATED: 7 Best Air Purifiers for Large Rooms — Breathe Deeper with No Fear!

Honeywell F100F2010 Media Air CleanerBest Central Air Purifier

  • Type: central
  • Square footage: all over the home HVAC system
  • Cleaning stages: 1
  • Size: 18 x 6 x 26 inches
  • Weight: 2 lbs
  • Filter type: MERV 11 filter
  • Warranty: not specified

More features: Applicable to all gas, oil and electric forced air furnaces, requires no electrical connections

Another central whole house air purifier at a great price, the Honeywell F100F2010 Media Air Cleaner is a good option for those who want to simply install the air purifier and let it do its thing without having to worry about too much maintenance or moving the device around from one place to another. This air purifier doesn’t need any electrical connections to work and is almost silent in operation, so you won’t even know it’s there, once it’s all installed.

A very efficient air purifier, the Honeywell F100F2010 Media Air Cleaner is equipped with strong filters to handle all those unwanted elements in the air. It’s fully compatible with all gas, oil, and electric forced air furnaces and it’s highly durable too, coated with zinc to resist corrosion. It features a MERV 11 filter, which isn’t quite as strong as a true HEPA filter, but still does enough to clean the air nicely.

As quite a cheap model, the Honeywell F100F2010 Media Air Cleaner doesn’t come with all the same features and functionality of some of the best portable air purifiers, like LED screens, timers, and various modes, but it’s an efficient and reliable all-round device that gives its owner a lot of value. It’s a good choice for those who want cleaner air without having to pay over the odds for the most impressive and feature-rich models.

What are our favorite features?

  • Good all-rounder
  • Minimal maintenance
  • Relatively simple installation
  • Compatible with all furnaces
  • Simple and efficient
  • Highly affordable

What could be better?

  • A bit basic
  • MERV 11 filter isn’t as strong as others

Airpura R600Best Portable Air Purifier

  • Type: portable
  • Square footage: 2000 sq ft
  • Cleaning stages: 3
  • Size: 23 x 15 x 15 inches
  • Weight: 47 lbs
  • Filter type: Anthracite Carbon Filter (100 % Blend), Impregnated Carbon Filter, (17% Potassium Iodide, 83% Coconut Shell Carbon) Main Particle Filter True HEPA filter
  • Warranty: 5-year limited parts and 10-year limited labor

More features: focuses on airborne particles and gases and odors, UVGI lamps

Last but not least, we come to the Airpura R600, another contender for the best whole house portable air purifier crown. Many users have enjoyed this air purifier for its thorough cleaning and filtration, featuring an anthracite carbon filter and a true HEPA filter, with a 3-stage cleaning process that fully eradicates almost all dirt, dust, pollen, allergens, and other unwanted elements in the air of your home. In short, if clean air is what you crave the most, the Airpura R600 is a terrific model to choose.

It’s excellent at reducing odors in the home too, leaving your house smelling fresh and clean at all times, and it comes with UV lamps to eliminate airborne microbes and protect your family’s health. It’s quite a quiet whole house air purifier too, and it can clean up to 2,000 square feet, so it’s a good option for many homes, but won’t work quite as well in larger properties.

The Airpura R600 comes with a high price tag and is a very heavy device, but it does have wheels for easy rolling around from room to room. All in all, it has a few flaws here and there, but it makes up for its issues with exceptionally powerful air filtration, offering some of the best results of any whole house air purifier on the market.

What stands out?

  • Very effective
  • Great against odors
  • Super strong filtration
  • UV lamps for microbes
  • Powerful 3-stage cleaning

What cons did we manage to find?

  • Very heavy and a bit difficult to move around
  • Quite a high price

Things to Consider

You’ve seen some of the best whole house air purifiers money can buy, but which one should you choose? The right answer will depend on the size of your home, the amount of money you want to spend, and the various features and factors that matter to you the most. This whole house air purifier buying guide will take you through all the details of finding the best purifier for you.

What benefits a whole house air purifier will bring to your health

A whole house air purifier can offer a lot of impressive benefits to your health and that of your family or other members of your household, including:

  • Asthma – If you, or anyone in your home, suffer from asthma, an air purifier can be a huge boost. The likes of dirt, dust, carbon monoxide, smoke, cosmetics, hairsprays, and mold spores can all trigger asthma attacks in the home. Air purifiers help to remove all these impurities.
  • Allergies – Air purifiers are also essential for those who suffer from allergies. Things like dust, pollen, pet hair, and more can float around in the air, being inhaled and triggering allergic reactions in those inside the home. An air purifier works to remove these allergens.
  • Smoke – If you have a smoker in the home and want to minimize their impact on other members of the family or visitors to the home, an air purifier with a HEPA filter, like the Coway Airmega 400 can work to rid the air of tobacco and cigarette smoke, protecting the respiratory systems of others.
  • Cleaner, Better Air – Whole house air purifiers can do a lot, ridding the air of many different pollutants, irritants, allergens, and undesirable elements. In short, they make the air cleaner for you to breathe, reducing your risks of a lot of different health problems from coughs and allergies all the way up to lung cancer.


Features to consider while choosing a whole house air purifier

If you’re thinking about buying a whole house air purifier, you need to take the time to do your research. There are various features to think about when considering which purifier to buy, and it’s vital to think about which of these features matter to you the most in order to find a product that fits all of your requirements.


Whole house air purifiers tend to come in two main categories: portable and central.

The central units have to be installed in a certain spot, while the portable whole house air purifiers can be moved around and placed in different areas, able to treat the air in your home in a more flexible way.

Many people choose portable whole house air purifiers, like the Airpura R600, due to their more convenient and versatile nature, but central units can be just as effective.

Square footage

This is one of the most important factors to think about. If you’re taking the time to invest in a whole house air purifier, it’s surely because you want your entire home to enjoy the benefits of clean air. This means you won’t want to waste money on a device that isn’t strong enough to handle the entire size of your property. Some whole house air purifiers are much more effective than others, able to handle higher amounts of square footage. The Green Air Deluxe 3 Plate HEPA, for example, can cover a space of 3,600 square feet.

Filter type

6 Best Whole House Air Purifiers - Reviews and Buying GuideThere are many different filter types that can be used in whole house air purifiers. One of the most common types of filter is the HEPA filter. These are also some of the best filters around. You can see HEPA filters in the Medify MA-112 Medical Grade True HEPA H13, for example. You can also see activated carbon filters in some whole house air purifiers. The carbon in these filters works to trap odors and gases, helping to clean up the air even more and making your home smell fresher and cleaner. There are UV light filters too, which work by killing microbes and even viruses, as well as ionizers and ozone generators that work to trap particles but can also pose risks to those with respiratory problems.

Cleaning stages

Each whole house air purifier has its own set of cleaning stages. Some will feature more stages than others. The Green Air Deluxe 3 Plate HEPA, for example, has a 4-stage cleaning process, while other models only offer one stage of cleaning. The number of stages isn’t always the most important thing, as the efficiency and effectiveness of each stage is what matters the most, but having additional stages is always a nice bonus.


The size of your whole house air purifier will be an important factor to think about for many people. These devices can be quite sizeable and take up a lot of space, and they can sometimes be quite heavy and hard to move around too, which can be difficult for those who want to get the full benefits of a portable whole house air purifier in a larger home. Some models are quite compact and lightweight, like the Green Air Deluxe 3 Plate HEPA, making them easier to manoeuvre around the house.


If you’re investing in something as important as a whole house air purifier, having the peace of mind that comes from a good warranty can make a big difference.

It’s always good to know that you’re covered in case of any unexpected faults or failures, but not every manufacturer offers the same standard of warranty.

The Medify MA-112 Medical Grade True HEPA H13 is one of the best whole house air purifiers you can choose in this respect, as it comes with a lifetime warranty, ensuring that your purifier will always be protected in case of any unforeseen issues.

Extra features

6 Best Whole House Air Purifiers - Reviews and Buying GuideSometimes, whole house air purifiers come along with some extra features and bonuses that can make them even more functional and versatile. They might feature a UV light, like the Green Air Deluxe 3 Plate HEPA for example, which helps to kill bacteria and other microbes in the air, while some of the Green Air models are even ionic air purifiers. They can also come with timer settings, as seen on the Coway Airmega 400, making them easier to use and giving you more precise control over their functionality. Some, like the Medify MA-112 Medical Grade True HEPA H13, can even come with features like sleep modes and child locks.

How to maintain a whole house air purifier

If you buy a whole house air purifier, you need to know how to look after so you don’t have to worry about getting it repaired or replaced in the future. If you choose a central device, like the Aprilaire 2410 Whole-Home Air Cleaner, you won’t have to worry too much about maintenance, as they tend to stay clean and functional without any problems. Portable purifiers require a little more care and will need to be cleaned now and then, depending on where you place them, but they aren’t too demanding. The main thing is to ensure that you change the filters on a regular basis. Most air purifiers come with indicators to let you know when to change the filter,


This depends on whether or not you buy a central or a portable unit. Central units have to be installed in specific areas. If you’re dealing with a portable air purifier, you need to be careful about where you place it. Choosing the wrong spot can reduce the purifier’s efficiency. A good choice is to identify an area that might be causing irritants in your home, like a window or an area that tends to smell or develop mold. Ideally, you don’t want to put the purifier under shelves, tucked away in corners, or near doors and windows that open a lot.

If you buy a good quality air purifier, you don’t need to worry about whether or not you have one, big open space or multiple rooms all connected. The best whole house air purifiers will be able to cover large spaces across interconnected rooms, cleaning the air throughout the whole property. Plus, since most of the best models are portable, you can always carry them around and take them into different rooms if you want more efficient air cleaning.

One of the common complaints regarding HEPA filters and other air purifier filters is that you have to throw them out and change them every now and then. Unfortunately, you can’t just wash these filters and put them back in. Washing may make them look cleaner to you, but on a microscopic level, they actually become way less effective and lose many of their particle-trapping fibers if you wash them.

Yes, this is a great benefit of many of the best whole house air purifiers. A lot of them are able to remove typical bad odor elements from the air like cigarette smoke and more. They work to trap unpleasant and unwanted particles commonly found in the air, leaving your house smelling fresher and the air you breathe being much cleaner too.

Our Verdict

Overall, our top-rated whole house air purifier is the Medify MA-112 Medical Grade True HEPA H13. With its medical-grade technology, powerful filtration, plenty of useful features, and even an attractive aesthetic, this air purifier has it all.

The next best whole house air purifier is the Green Air Deluxe 3 Plate HEPA. Equipped with a range of great features like timers and an LCD display, this air purifier is particularly effective at dealing with odors, pet hairs, dust, and allergens. It’s one of the most thorough purifiers around, offering a 4-stage cleaning process and some of the strongest filtration you could hope to find.

Our third favorite whole house air purifier is the Aprilaire 2410 Whole-Home Air Cleaner. The best value unit we could find, this one requires barely any maintenance whatsoever, letting you simply install it and walk away, safe in the knowledge that the air of your home is a lot cleaner.

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